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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $195 | In Stock | |
2 mg | $293 | In Stock | |
5 mg | $447 | In Stock | |
10 mg | $659 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | $1,380 | In Stock | |
100 mg | $1,890 | In Stock | |
500 mg | $3,790 | In Stock | |
1 mL x 10 mM (in DMSO) | $431 | In Stock |
Description | (E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors. |
In vitro | (E)-GABAB receptor antagonist 1 reduces the maximum effect of IP3 in HEK293 cells overexpressing GABAB receptor and Gqi9 protein induced by agonist GABA, but does not alter EC50[1]. |
Molecular Weight | 304.38 |
Formula | C18H24O4 |
Cas No. | 1611483-29-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (164.27 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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